Bioss Inc.'s Topoisomerase II beta Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen. The Topoisomerase II beta Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated was generated using TOP2B as the antigen and it reacts with Human, and Rat.
Description
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Indirectly ivolved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene